Monday 11 March 2019

What patients are considered high risk patients for IV contrast for CIN?

This answer is very broad but here are some typical responses :

  • The patient with a history of renal disease especially if the patient is a diabetic
  • A patient on certain known nephrotoxic drugs such as aminoglycosides and amphotericin B
  • Dehydrated patients regardless of the cause
  • Patients with poor cardiac status including congestive heart failure
  • Patients with multiple myeloma
  • Patients with recent contrast injection of more than 100-120 ml in the preceding 24 hours (potential increased risk)
Recent articles question ehether iodinated contrast alone is really a risk factor for CIN. Many articles now question if not giving IV contrast when needed actually puts the patient at greater risk than giving it. Stayed tuned for further updates.

"Intravenous contrast material administration was not associated with excess risk of AKI acute kidney injury , dialysis, or death, even among patients with comorbidities reported to predispose them to nephrotoxicity."
Intravenous contrast material exposure is not an independent risk factor for dialysis or mortality.

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