Two common regimens are the use of bicarbonate in solution as part of a prestudy ( and often post study protocol) hydration protocol.
Use of N-Acetylcysteine (meta-analysis showed no advantage although recent article was more positive about its use)
Prevention Strategies
- Hydrate to a target urine output of 150 mL/h in the 6 hours postprocedure
- Avoid nephrotoxic drugs
- Use prophylactic pharmacologic agents or procedures (eg, NAC, statins, ascorbic acid, hemofiltration)?
- Minimize volume of CM
- Consider choice of CM
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