Monday, 8 July 2019

Is it ok for patients to have both an MR and a CT with contrast on the same day

This question was addressed on the RSNA site and there is no issue doing both MRI and CT the same day with Gadolinium and Iodinated Contrast.
Here is more detailed information courtesy of Richard A. Vitti MD from Medical Affairs at GE Healthcare.
CT contrast, or X-ray contrast for IV use, is usually an iodinated compound, whereas most MRI contrast media contains a heavy metal ion usually gadolinium. Iodine provides contrast by virtue of absorption of X-rays at the K-edge. Gd provides contrast in MR by changing the magnetic moment. Generally these agents distribute themselves from the vascular space to the interstitial space of soft tissues, and are elminated by glomerular filtration by the kidneys. 

Are there any contrast volume limitations for the use of IV contrast?

Traditionally contrast dose for adult body CT is given in ranges of 50ml – 200ml, depending on procedure (hepatic, renal…) and iodine concentration (270mgI/ml to 400 mgI/ml). With increasing awareness of CIN and radiation dose, the trend has started to shift toward contrast dose by body weight. Some device manufacturers like Medrad (P3T) have introduced power injectors that follow a dose by weight protocol. There are a few studies published on weight-based dose for adults. Below are several examples.

Sunday, 7 July 2019

What the meaning of GFR ?

 Glomerular Filtration Rate (GFR) and Creatinine Clearance (CrCl) in Health and Disease: Using Popular Formulae (September 2009) 

Sunday, 28 April 2019

CSF flow studies

CSF flow studies are performed using a variety of MRI techniques and are able to qualitatively assess and quantify pulsatile CSF flow. The most common technique used is time-resolved 2D phase contrast MRI with velocity encoding. 

Monday, 8 April 2019

MRI pulse sequence abbreviations

This article contains a list of commonly and less commonly used MRI pulse sequence abbreviations and their meaning. If available, an explanation is included in a separate article.

MRI sequence

An MRI sequence is a number of radiofrequency pulses and gradients that result in a set of images with a particular appearance. This article presents a simplified approach to recognizing common MRI sequences, but does not concern itself with the particulars of each sequence.
For a more complete and accurate discussion please refer to MRI pulse sequences.

MRI safety

MRI scanners, although free from potentially cancer-inducing ionising radiation found in plain radiography and CT, have a host of safety issues which must be taken very seriously. MRI safety can be divided into:
  1. main magnetic field
  2. varying magnetic (gradient) fields
  3. radiofrequency